Abstract: Radio telescopes are vulnerable to the Earth’s artificial electromagnetic signal interference. In order to protect the electromagnetic environment of Five-hundred-meter Aperture Spherical radio Telescope (FAST), the mobile base station interference detection experiment was carried out. By compatibility analyzing the electromagnetic of single and multiple base stations and FAST, and combining the propagation loss around the telescope, the measures to reduce the interference of base stations and ensure the communication demand of surrounding residents are studied, providing useful suggestions for reducing the interference of base stations.