Abstract: In this paper, the target selection and trajectory optimization is investigated for manned asteroid exploration mission in 2020一2040. Firs街，According to various factors and constraints , such as absolute magnitude and orbital parameters, 20 potential candidates for manned missions are presented. And then, the design model for manned mission is constructed, and the exploration trajectories for asteroid candidates are computed场using parameters optimization algorithm directly. Furthermore, the prime vector theory is used to obtain the optimal exploration trajectories. This research can provide valuable proposals for future manned asteroid missions