Abstract: In this paper, the QH-E（Qinghua-E sample）lunar soil simulant was taken as the research object, and a temperature dependent cohesive tensor was introduced based on the Gudehus-Bauer hypoplastic model framework to establish a hypoplastic constitutive model coupled with temperature effects. By comparing the model results with physical experiments, the effectiveness of the model was verified, achieving a unified characterization of the strain softening and compressive hardening response of lunar soil under deep ultra-low temperature environmental conditions on the lunar surface. The deformation characteristics such as shear dilation/contraction transition and critical state approaching were effectively simulated, reflecting the significant influence of temperature on the mechanical properties of lunar soil simulant. Compared with traditional elastoplastic models, the hypoplastic model coupled with temperature effects in this paper can effectively reveal the strength and deformation characteristics of lunar soil in the lunar environment, and better reflect the inherent influence of temperature on the strength and deformation evolution mechanism of lunar soil simulant. It provides theoretical support for engineering problems such as stability analysis of lunar landers and construction of lunar base.