Abstract: In this paper, the QH-E（Qinghua-E sample） lunar soil simulant is taken as the research object, and a temperature dependent cohesive tensor is introduced based on the Gudehus-Bauer hypoplastic model framework to establish a hypoplastic constitutive model coupled with temperature effects. By comparing the model results with physical experiments, the effectiveness of the model is verified, achieving a unified characterization of the strain softening and compressive hardening response of lunar soil under deep low temperature environmental conditions on the lunar surface. The deformation characteristics such as shear dilation/contraction transition and critical state approaching are effectively simulated, reflecting the significant influence of temperature on the mechanical properties of lunar soil simulant. Compared with traditional elastoplastic models, the hypoplastic model coupled with temperature effects in this paper can effectively reveal the strength and deformation characteristics of lunar soil in the lunar environment, and can better reflect the inherent influence of temperature on the strength and deformation evolution mechanism of lunar soil simulant. It provides theoretical support for engineering problems such as stability analysis of lunar lander and construction of lunar base.