An autonomous guidance,navigation and control(GNC)scheme based on multi-information fusion is proposed for Mars pinpoint landing mission. Before entering the Mars atmosphere,an autonomous navigation scheme fusing X-Ray pulsars and Mars landmark images is employed to satisfy the requirement of high precision navigation. Then,during Mars entry,descent and landing(EDL)phase,a multi-information fusion navigation scheme is constructed for absolute and relative navigation with high precision, which consists of Mars landmark images, inertial measurement unit (IMU) and ranging and velocity sensors. With the demands of pinpoint landing, a guidance and control algorithm is also designed for Mars atmosphere entry phase and powered descent phase. Finally,numerical simulation is performed,which indicates that the landing accuracy is better than 100 m and the hazard avoidance accuracy is around 0.5 m when adopting the proposed GNC scheme.