Abstract: The launch vehicle structure, as one of the important systems of launch vehicle, is the foundation of launch vehicle and directly relates to the overall performance of the launch vehicle. A series of technical problems are faced with the huge leap from Φ3.35 m to Φ5 m in the product size of the launch vehicle structure. To solve these problems, a set of theoretical and methodological system suitable for the design of the Φ5 m launch vehicle structure products is established by adopting innovative design concept. At the same time, the upgrading of the material system of launch vehicle structure is vigorously promoted. With the implementation of these methods, the product system of the Φ5m launch vehicle structure, and the fine design and multi-function integrated design of the Φ5 m launch vehicle structure are realized.