Abstract: Limited by the loading capability of launch vehicle, the deep space probe is required to reduce its own weight. Based on the most advanced space power supply technology in China, the power supply and distribution system of Chang’e-5 orbiter adopts ultra-high energy density solar cells and batteries, and invents a new bus topology. Through a series of lightweight power distribution system design, the power to weight ratio of the whole probe reaches the domestic leading level. The power supply and distribution system of spacecraft has passed the ground verification and flight test on in orbit, therefore can be referred for the follow-up research and design of high specific energy of power supply and distribution system of spacecraft.